原著・総説 2011~2014

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  【 2014 】
1. Rokugawa T, Uehara T, Higaki Y, Matsushima S, Obata A, Arano Y, Abe K.
Potential of 99mTc-MIBI SPECT imaging for evaluating non-alcoholic steatohepatitis induced by methionine-choline-deficient diet in mice.
EJNMMI Research, 4: 57 (2014) .
2. K. Higashikawa, K. Yagi, K. Watanabe, S. Kamino, M. Ueda, M. Hiromura, S. Enomoto.
64Cu-DOTA-anti-CTLA-4 mAb enabled PET visualization of CTLA-4 on the T-cell infiltrating tumor tissues.
PLoS One, vol. 9; 11 e109866. (2014).
3. S. Kamino, M, Murakami, M, Tanioka, Y. Shirasaki, K. Watanabe, J. Horigome, Y. Ooyama, S. Enomoto.
Design and Syntheses of Highly Emissive Aminobenzopyrano-xanthene Dyes in the Visible and Far-Red Regions.
Org. Lett., 16 (1), 258-261 (2014).
4. Ueda M, Saji H.
Radiolabeled probes targeting hypoxia-inducible factor-1-active tumor microenvironments.
The Scientific World Journal, 2014: 165461 (2014).
5. Ueda M, Fukushima T, Ogawa K, Kimura H, Ono M, Yamaguchi T, Ikehara Y, Saji H.
Synthesis and evaluation of a radioiodinated peptide probe targeting αvβ6 integrin for the detection of pancreatic ductal adenocarcinoma.
Biochem. Biophys. Res. Commun., 445(3): 661-6 (2014).
6. Kobayashi M, Nakanishi T, Nishi K, Higaki Y, Okudaira H, Ono M, Tsujiuchi T, Mizutani A, Nishii R, Tamai I, Arano Y, Kawai K.
Transport Mechanisms of Hepatic Uptake and Bile Excretion in Clinical Hepatobiliary Scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan.
Nucl. Med. Biol., 2014; 41(4):338-42.
7. 佐治英郎、上田真史、木村寛之.
総説1 核医学・分子イメージング
核医学分子イメージングのための放射性分子プローブの戦略的設計.
PETジャーナル第25号.17-20 (2014).
8. 東川桂、上田真史、本村信治、榎本秀一.
癌と炎症の複数分子イメージング:消化器系疾患への応用の可能性.
G.I.Research. 22(1): 57-63 (2014).
9. 谷口将済、榎本秀一、廣村信.
亜鉛トランスポーターZIP9によるB細胞受容体シグナルの活性化制御.
YAKUGAKU ZASSHI, 134(7) ,809-812, (2014).
10. 宮本昂明、神野伸一郎、小谷明、廣村信、榎本秀一.
64Cuによる部位特異的放射標識を目的とした新規ペプチド性キレート剤の開発.
YAKUGAKU ZASSHI, 134(7) ,797-800, (2014).
11. 廣村信、榎本秀一.
亜鉛による免疫機能制御-栄養素から情報伝達分子へ.
週刊医学のあゆみ, 249(7), 623-624 (2014).
  【 2013 】
1. T. Urabe, K. Takahashi, M. Kitagawa, T. Sato, T. Kondo, S. Enomoto, M. Kidera, Y. Seto.
Development of portable mass spectrometer with electron cyclotron resonance ion source for detection of chemical warfare agents in air.
Spectrochim. Acta A, 120, 437-44 (2013).
2. T. Miyamoto, S. Kamino, A. Odani, M. Hiromura, S. Enomoto.
Basicity of N-terminal amine in ATCUN peptide regulates stability constant of albumin-like Cu2+ complex.
Chem. Lett., 42, 1099-1101 (2013).
3. Y. Shirasaki, S. Kamino, M. Tanioka, K. Watanabe, Y. Takeuchi, S. Komeda, S. Enomoto.
New aminobenzopyranoxanthene-based colorimetric sensor for Cu2+ with dual-color signal detection system.
Chem. Asian J., 8, 2609-2613 (2013).
4. S. Motomura, Y. Kanayama, M. Hiromura, T. Fukuchi, T. Ida, H. Haba, Y. Watanabe, S. Enomoto.
Improved imaging performance of semiconductor Compton camera GREI makes for a new methodology to integrate bio-metal analysis and molecular imaging technology in living organisms.
J. Anal. At. Spectrom. , 28, 934-939 (2013).
5. S. Kadowaki, M. Munekane, Y. Kitamura, M. Hiromura, S. Kamino, Y. Yoshikawa, H. Saji, S. Enomoto.
Development of new zinc dithiosemicarbazone complex for use as oral antidiabetic agent.
Biol. Trace Elem. Res., 154, 111-119 (2013).
6. M. Taniguchi, A. Fukunaka, M. Hagihara, K. Watanabe, S. Kamino, T. Kambe, S. Enomoto, M. Hiromura.
Essential role of the zinc transporter ZIP9/SLC39A9 in regulating the activations of Akt and Erk in B-cell receptor signaling pathway in DT40 cells.
PLoS One, vol. 8; 3 e58022. (2013).
7. S. Kamino, A. Muranaka, M. Murakami, A. Tatsumi, N. Nagaoka, Y. Shirasaki, K. Watanabe,, K. Yoshida, J. Horigome, S. Komeda, M. Uchiyama, S. Enomoto.
A Red-Emissive aminobenzopyrano-xanthene Dye: Elucidation of Fluorescence Emission Mechanism in Solution and Aggregate State.
Phys. Chem. Chem. Phys., 15, 2131-2140 (2013).
8. Ogawa K, Ohtsuki K, Shibata T, Aoki M, Nakayama M, Kitamura Y, Ono M, Ueda M, Doue T, Onoguchi M, Shiba K, Odani A.
Development and evaluation of a novel 99mTc-labeled annexin a5 for early detection of response to chemotherapy.
PLoSOne. 8(12): e81191 (2013).
9. Ueda M, Ogawa K, Miyano A, Ono M, Kizaka-Kondoh S, Saji H.
Development of an oxygen-sensitive degradable peptide probe for the imaging of hypoxia-inducible factor-1-active regions in tumors.
Mol. Imaging Biol., 15(6): 713-21 (2013).
10. Yanagi M, Uehara T, Uchida Y, Kiyota S, Kinoshita M, Higaki Y, Akizawa H, Hanaoka H, Arano Y.
Chemical design of 99mTc-labeled probes for targeting osteogenic bone region.
Bioconjug Chem., 2013; 24(7):1248-55.
11. 佐治英郎、上田真史、木村寛之.
生体分子イメージングのための放射性分子プローブの戦略的分子設計.
日本分子イメージング学会機関誌.7(1): 11-15 (2013).
12. 榎本秀一、本村信治.
半導体コンプトンカメラ“GREI”による分子イメージング研究の展開.
Isotope News, 12, 2-6 (2013).
13. 榎本秀一.
メタロミクス研究に資する分子イメージング技術開発生体内金属のダイナミクスの可視化.
科研費 News, 4, 17 (2013).
14. 神山伸、曽根英行、石黒真理子、榎本秀一.
大腸癌細胞におけるSLC35F5 輸送体の発現と5-fluorouracil 感受性について.
人間生活学研究, 4,137-145 (2013).
  【 2012 】
1. T. Okada, M. Hiromura, M. Otsuka, S. Enomoto H. Miyachi.
Synthesis of BMS-309403-Related Compounds, Including [14C]BMS-309403, a Radioligand for Adipocyte Fatty Acid Binding Protein.
Chem. Pharm.  Bull., 60(1), 164-168 (2012).
2. S. Takeda, H. Odaka, S. Ishikawa, S. Watanabe, H. Aono, T. Takahashi, Y. Kanayama, M. Hiromura, S. Enomoto.
Demonstration of in-vivo multi-probe tracker based on a Si/CdTe semiconductor Compton camera.
IEEE Trans. Nucl. Sci., 59, 70-76 (2012).
3. 小野正博、上田真史、佐治英郎.
アルツハイマー病の診断と治療の最先端
アルツハイマー病PET診断薬開発の最先端.
PETジャーナル第19号.13-5 (2012).
4. 御舩正樹、岩藤章正、神野伸一郎、榎本秀一.
Octabromo-tetrakis(4-methylpyridyl)porphine を用いる銅イオンの吸光光度定量
YAKUGAKU ZASSHI, 132(8), 953-958 (2012).
5. 上田真史.
プレターゲット法を利用した腫瘍内低酸素誘導因子存在領域の高精度核医学分子イメージング法の開発
YAKUGAKU ZASSHI, 132(5): 595-600 (2012).
6. 神山伸、曽根英行、榎本秀一.
SLC35Fファミリー遺伝子の取得と機能解析.
人間生活学研究, 3, 19-25 (2012).
7. 谷口将済、神野伸一郎、廣村信、榎本秀一.
生体微量金属元素のダイナミクスと複数分子イメージング.
分析化学, 61(12), 1013-1025 (2012).
8. 神野伸一郎、榎本秀一.
「新たなp共役拡張型色素化合物アミノベンゾピラノキサンテン系蛍光色素 「ABPX」の開発」
月刊機能材料, 32, 59-64 (2012).
  【 2011 】
1. K. Yamasaki, Y. Sakuma, J. Sasaki, K. Matsumoto, K. Anzai, K. Matsuoka, C. Honda, M. Tsukada, K. Endo, S. Enomoto.
Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency.
Anal. Bioanal. Chem., 401, 2531-2538 (2011).
2. M. Mifune, A. Iwado, M. Taniguchi, S. Kamino, S. Enomoto.
Photometric study on the reaction between 2,3,7,8,12,13,17,18-octabromo-5,10,15,20-tetrakis-(4-methylpyridyl)porphine and various metal ions.
Yakugaku Zasshi-J. Pharm. Soc. Jpn., 131, 1233-1240 (2011).
3. K. Higashikawa, N. Akada, K. Yagi, K. Watanabe, S. Kamino, Y. Kanayama, M. Hiromura, S. Enomoto.
Exploration of target molecules for molecular imaging of inflammatory bowel disease.
Biochem. Biophys. Res. Commun., 410, 416-421 (2011).
4. H. Fujishiro, M. Doi, S. Enomoto, S. Himeno.
High sensitivity of RBL-2H3 cells to cadmium and manganese: an implication of the role of ZIP8.
Metallomics, 3, 710-718 (2011).
5. A. Fukunaka, Y. Kurokawa, F. Teranishi, I. Sekler, K. Oda, M. L. Ackland, V. Faundez, M. Hiromura, S. Masuda, M. Nagao, S. Enomoto, T. Kambe.
Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway.
J. Biol. Chem., 286, 16363-16373 (2011).
6. T. Fukuchi, Y. Arai, F. Watanabe, S. Motomura, S. Takeda, Y. Kanayama, H. Haba, Y. Watanabe, S. Enomoto.
A digital signal processing module for Ge semiconductor detectors.
IEEE Trans. Nucl. Sci., 58, 461-467 (2011).
7. M. Kidera, Y. Seto, K. Takahashi, S. Enomoto, S. Kishi, M. Makita, T. Nagamatsu, T. Tanaka, M. Toda.
New method for comprehensive detection of chemical warfare agents using an electron-cyclotron-resonance ion-source mass spectrometer.
Spectroc. Acta Pt. A-Molec. Biomolec. Spectr., 78, 1215-1219 (2011).
8. H. Fujishiro, K. Kubota, D. Inoue, A. Inoue, T. Yanagiya, S. Enomoto, S. Himeno.
Cross-resistance of cadmium-resistant cells to manganese is associated with reduced accumulation of both cadmium and manganese.
Toxicology, 280, 118-125 (2011).
9. F. Yatagai, M. Honma, A. Takahashi, K. Omori, H. Suzuki, T. Shimazu, M. Seki, T. Hashizume, A. Ukai, K. Sugasawa, T. Abe, N. Dohmae, S. Enomoto, T. Ohnishi A. Gordon, N. Ishioka.
Frozen human cells can record radiation damage accumulated during space flight: mutation induction and radioadaptation.
Radiat. Environ. Biophys., 50, 125–134 (2011).
10. H. Kikunaga, T. Yoshimura, T. Kuribayashi, Y. Kitamoto, N. Takahashi, H. Haba, Y. Ezaki, S. Enomoto, T. Mitsugashira, A. Shinohara.
Separation of Am(III), Cm(III), and Cf(III) using capillary electrophoresis.
Proc. Radiochim. Acta, 1,167-171 (2011).